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 MOLECULAR BASIS OF INHERITANCE. NCERT Based & Simplified 1. Finding out the chemical responsible for Mendelian inheritance (factor), its structure,& How it works is  MOLECULAR BASIS OF INHERITANCE. 2. DNA act as genetic material in all cellular organism either it is prokaryotic or eukaryotic. o RNA ACT AS GENETIC MATERIAL ONLY IN SOME VIRUSES. o RNA also act as messenger ,adaptor & structural RNA. o RNA also act as enzyme molecule(Ribozyme) @ RNA World Hypothesis 3. THE DNA ●Polymer of Nucleotide -->POLYNUCLEOTIDE ●The length of DNA is expressed in base pair (bp) ●Specific for particular organism. ●Bp is number of nucleotide pairs in DNA ●Bacteriophage -Φ174 5386 nucleotides. ●Bacteriophage -->48502 bp ●E.coli --> 4.6x106 bp ●Human -->3.3 x109 bp in haploid cell. 4. BUILDING BLOCK OF NUCLEIC ACID and NUCLEOTIDE o A nucleotide has three component -a nitrogenous base (either purine or pyrimidine) ,deoxyribose pentose sugar& a p

BODY FLUID & CIRCULATION   1. BLOOD  o Study of blood is called Haematology. o Blood originates from Mesoderm. o Blood formation is called Hemopoiesis and in adult human it takes place in BONE MARROW but during embryonic state it takes place mainly in liver (little blood also form in spleen and rib in embryo). o Blood pH-7.4. o Blood volume in a person is 1/13th part of total body weight. o Special connective tissue o Consisting of a fluid matrix, plasma, and formed elements. 2. PLASMA o Straw coloured. Viscous fluid. o Organic component of plasma is Constituting nearly 55 per cent of the blood. o 90-92 per cent water + proteins 6-8 percent of it. o Fibrinogen, globulins and albumins are the major proteins. o Anticoagulant heparin is secreted by Mast cells prevent blood clotting in blood vessels. o FIBRINOGENS are needed for clotting or coagulation of blood. o GLOBULINS primarily are involved in defence mechanisms of the body o ALBUMINS help in